Copper-64 labeled liposomes for imaging bone marrow
نویسندگان
چکیده
منابع مشابه
PET imaging of CXCR4 using copper-64 labeled peptide antagonist
Expression of CXCR4 in cancer has been found to correlate with poor prognosis and resistance to chemotherapy. In this study we developed a derivative of the CXCR4 peptide antagonist, T140-2D, that can be labeled easily with the PET isotope copper-64, and thereby enable in vivo visualization of CXCR4 in tumors. T140 was conjugated to 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid mono ...
متن کاملNano Liposomes labeled with 99mTc-HMPAO, A Novel Agent for Blood Pool Imaging
In-vitro labeling of RBC with 99mTc is an intricate procedure and there is always a need foran alternate blood pool imaging agent. The aim of this study was to prepare an effective nanosized liposome (NLs) similar to human RBC for blood pool scintigraphy. This study formulatesPEG-NLs and non-PEG-NLs using film method plus high pressure homogenization technique.Biodistribution studies were perfo...
متن کاملNano Liposomes labeled with 99mTc-HMPAO, A Novel Agent for Blood Pool Imaging
In-vitro labeling of RBC with 99mTc is an intricate procedure and there is always a need foran alternate blood pool imaging agent. The aim of this study was to prepare an effective nanosized liposome (NLs) similar to human RBC for blood pool scintigraphy. This study formulatesPEG-NLs and non-PEG-NLs using film method plus high pressure homogenization technique.Biodistribution studies were perfo...
متن کاملMolecular imaging with copper-64.
Molecular imaging is expected to change the face of drug discovery and development. The ability to link imaging to biology for guiding therapy should improve the rate at which novel imaging technologies, probes, contrast agents, drugs and drug delivery systems can be transferred into clinical practice. Nuclear medicine imaging, in particular, positron emission tomography (PET) allows the detect...
متن کاملClinical significance of additional lateral imaging in diagnosis of prosthesis infection by combined Tc-99m labeled leukocyte/bone marrow scintigraphy
Introduction: Recently the most accurate diagnostic method in the diagnosis of prosthesis infection is the combination of Tc-99m labeled leukocyte/bone marrow imaging. However the diagnostic efficiency of the test is influenced because of its low spatial resolution. Recently SPECT/CT imaging is implicated in this test with efficient additional diagnostic improvement. In the dep...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nuclear Medicine and Biology
سال: 2016
ISSN: 0969-8051
DOI: 10.1016/j.nucmedbio.2016.08.011